IP6K3 Antibody

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

IP6K3 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence RLCSEYPENKRHR corresponding to internal region according to NP_473452.2.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IP6K3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave an approx. 37 kDa band in human brain (cerebral cortex and hippocampus) and mouse brain lysates after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 46.4 kDa band according to NP_473452.2. The 37 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for IP6K3 Antibody

• IHPK3ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
• inositol hexakisphosphate kinase 3
• Inositol hexaphosphate kinase 3EC 2.7.4.21
• InsP6 kinase 3
• INSP6K3MGC102928

Background

IP6K3, also known as Inositol hexakisphosphate kinase 3, is a 46 kDa 410 amino acid protein, and is involved in the transformation of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate. This protein has also been shown to have interactions with HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, and HIST1H2BI in the inositol pyrophosphates biosynthesis and metabolism pathway. Disease research is currently being studied with relation to IP6K3 and lupus erythematosus and malaria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IP6K3 Antibody (NBP1-45229)(1)

Publication using NBP1-45229

• Saiardi A, Nagata E, Luo HR et al. Identification and characterization of a novel inositol hexakisphosphate kinase J Biol Chem 2001-10-01 [PMID: 11502751]

Bioinformatics

• Gene Symbol: IP6K3
• Entrez:
  • 117283(Human)
  • 271424(Mouse)
  • 688862(Rat)
• Uniprot:
  • NP_473452.2(Human)