INPP5A 293T Cell Transient Overexpression Lysate

Product Discontinued

INPP5A 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-INPP5A antibody by Western Blots. Plasmid: pCMV-INPP5A full-length
• Specificity: INPP5A 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: INPP5A

Applications/Dilutions

• Dilutions:
  • Western Blot
• Theoretical MW: 40 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for INPP5A 293T Cell Transient Overexpression Lysate

• 43 kDa inositol polyphosphate 5-phophatase
• CTCL tumor antigen HD-CL-02,5PTASE
• DKFZp434A1721
• EC 3.1.3.56
• inositol polyphosphate-5-phosphatase, 40kD
• inositol polyphosphate-5-phosphatase, 40kDa
• inositol trisphosphate-5-phosphatase, 40kD
• InsP3 5-phosphatase
• MGC116947,5PTase
• MGC116949
• type I inositol-14,5-trisphosphate 5-phophatase
• type I inositol-14,5-trisphosphate 5-phosphatase

Background

INPP5A is a gene which codes for a protein that functions as a major isoenzyme that hydrolyzes the calcium-mobilizing second messenger Ins(1,4,5)P3 in a signal-terminating reaction and is comprised of 412 amino acids, with a mass of approximately 48 kDa. Studies are being conducted in several diseases and disorders relating to this gene including oculocerebrorenal syndrome, cutaneous T cell lymphoma, squamous cell carcinoma, Fanconi syndrome, schizophrenia, carcinoma, and olivopontocerebellar atrophy. INPP5A has also been shown to have interactions with PLEK, YWHAZ, GRB2, INPP1, and IPMK in pathways such as the inositol phosphate metabolism pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: INPP5A