INO80 Antibody

• Reactivity: Hu, Rt, Bv, Ca
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

INO80 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-TQEDYDSNHFKAQ corresponding to internal region according to NP_060023.1.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: INO80
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:4000
• Application Notes: WB: Preliminary experiments in human brain (cerebellum) and human testis lysates and in lysates of HeLa and K562 gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for INO80 Antibody

• EC 3.6.1
• EC 3.6.1.23
• EC 3.6.4.12
• hINO80INO80 complex subunit A
• homolog of yeast INO80
• INO80 complex homolog 1 (S. cerevisiae)
• INO80 homolog (S. cerevisiae)
• Ino80
• INO80A
• INOC1putative DNA helicase INO80 complex homolog 1
• KIAA1259

Background

INOC1 is the human homolog of S. cerevisiae Ino80, the catalytic ATPase subunit of the INO80 chromatin remodeling complex (Shen et al., 2000 (PubMed 10952318); Bakshi et al., 2004 (PubMed 15207721)). INOC1 defines a subfamily of SWI2/SNF2 chromatin remodeling proteins; see SMARCA (MIM 600014) for background information.(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for INO80 Antibody (NBP1-46157)(1)

Publication using NBP1-46157

• Yao T, Song L, Jin J et al. Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell 2008-09-01 [PMID: 18922472]

Bioinformatics

• Gene Symbol: INO80
• Entrez:
  • 54617(Human)
  • 68142(Mouse)
  • 296084(Rat)
• Uniprot:
  • Q9ULG1(Human)
  • Q6ZPV2(Mouse)