ILT1/CD85h/LILRA2 Antibody (600002) [Biotin]

Product Discontinued

ILT1/CD85h/LILRA2 Antibody (600002) [Biotin] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRA2/CD85h/ILT1
  Pro17-Ser437
  Accession # Q8N149
• Specificity: Detects human LILRA-2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) LILRA-1, rhLILRA-3, rhLILRA-4, rhLILRA-5, rhLILRA-6, rhILT-2, rhILT-4, or rhILT-5 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB63641. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for ILT1/CD85h/LILRA2 Antibody (600002) [Biotin]

• CD85 antigen-like family member H
• CD85h antigen
• CD85h
• ILT1
• ILT-1
• ILT1CD85H
• Leukocyte immunoglobulin-like receptor 7
• leukocyte immunoglobulin-like receptor subfamily A member 2 soluble
• leukocyte immunoglobulin-like receptor subfamily A member 2
• leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
• LILRA2
• LIR7
• LIR7LIR-7Immunoglobulin-like transcript 1

Background

LILRA2, also known as Leukocyte immunoglobulin-like receptor subfamily A member 2, has a 483 amino acid long isoform that is 53 kDa and a short 466 amino acid isoform that is 51 kDa, acts as an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport, but does not bind class I MHC antigens. Studies are being performed in relation to this protein and several diseases and disorders including leprosy, microscopic polyangiitis, systemic lupus, erythematosus, lupus erythematosus, hepatitis c, and hepatitis b. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.