Human IL-29/IFN-lambda 1 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-29/IFN-lambda 1 DuoSet ELISA, 15 Plate Summary

• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IFNL1

Applications/Dilutions

• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-29/IFN-lambda 1 DuoSet ELISA, 15 Plate

• cytokine Zcyto21
• IFNL1
• IFN-lambda 1
• IFN-lambda-1
• IL29
• IL-29
• interferon lambda-1
• interferon, lambda 1
• interleukin 29 (interferon, lambda 1)
• interleukin-29
• ZCYTO21

Background

Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Publications for IL-29/IFN-lambda 1 (DY7246)(5)

Publications using DY7246

• S Albertini, I Lo Cigno, F Calati, M De Andrea, C Borgogna, V Dell'Oste, S Landolfo, M Gariglio HPV18 Persistence Impairs Basal and DNA Ligand-Mediated IFN-? and IFN-?Production through Transcriptional Repression of Multiple Downstream Effectors of Pattern Recognition Receptor Signaling J. Immunol., 2018;0(0):. 2018 [PMID: 29386255] (Human)
• J Corry, N Arora, CA Good, Y Sadovsky, CB Coyne Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal-fetal interface Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):. 2017 [PMID: 28784796] (Human)
• MC Mladinich, J Schwedes, ER Mackow Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells MBio, 2017;8(4):. 2017 [PMID: 28698279] (Human)
• Travanty E, Zhou B, Zhang H, Di Y, Alcorn J, Wentworth D, Mason R, Wang J Differential Susceptibilities of Human Lung Primary Cells to H1N1 Influenza Viruses. J Virol, 2015;89(23):11935-44. 2015 [PMID: 26378172] (Human)
• Wu Q, Jiang D, Huang C, van Dyk L, Li L, Chu H Trehalose-mediated autophagy impairs the anti-viral function of human primary airway epithelial cells. PLoS ONE, 2015;10(4):e0124524. 2015 [PMID: 25879848] (Human)

FAQs for IL-29/IFN-lambda 1 (DY7246). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IFNL1