Human DPPIV/CD26 DuoSet ELISA, 15 Plate



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

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Human DPPIV/CD26 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY1180.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human DPPIV/CD26 DuoSet ELISA, 15 Plate

  • ADCP-2
  • Adenosine deaminase complexing protein 2TP103
  • CD26 antigen
  • CD26
  • CD26T-cell activation antigen CD26
  • dipeptidyl peptidase 4
  • Dipeptidyl peptidase IV
  • dipeptidylpeptidase 4
  • dipeptidyl-peptidase 4
  • dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
  • DPP4
  • EC


DPPIV/CD26 is a serine exopeptidase that is expressed as a noncovalent homodimer on the surface of epithelial cells, endothelial cells, and activated lymphocytes. It regulates multiple aspects of immune and endocrine function by cleaving Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of a wide variety of chemokines (CCL4 and 5, CXCL6, 9, 10, 11, and 12), growth factors (GM-CSF, IL-3), and peptide hormones (Glucagon, Glucagon-like Peptides 1 and 2, GIP, GHRH, Procalcitonin, Neuropeptide Y, and Substance P). DPPIV interacts in cis with Adenosine Deaminase on T cells, in trans with Caveolin-1 on antigen presenting cells, and it serves as a cell entry coreceptor for HIV and coronavirus. It provides costimulatory proliferation and activation signals to both CD4+ and CD8+ T cells. A soluble form of DPPIV can be proteolytically shed from adipocytes, leading to insulin resistance in adipocytes and skeletal muscle.

Publications for DPPIV/CD26 (DY1180)(12)

We have publications tested in 1 confirmed species: Human.

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Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using DY1180 Applications Species
Höpfinger, A;Karrasch, T;Schäffler, A;Schmid, A; Circulating Concentrations of Cathelicidin Anti-Microbial Peptide (CAMP) Are Increased during Oral Glucose Tolerance Test International journal of molecular sciences 2023-08-17 [PMID: 37629082] (Human) Human
Höpfinger, A;Karrasch, T;Schäffler, A;Schmid, A; Circulating Levels of Cathelicidin Antimicrobial Peptide (CAMP) Are Affected by Oral Lipid Ingestion Nutrients 2023-07-03 [PMID: 37447348] (Human) Human
OJ Cordero, C Rafael-Vid, R Varela-Cal, C Calviño-Sa, B Malvar-Fer, S García, JE Viñuela, JM Pego-Reigo Distinctive CD26 Expression on CD4 T-Cell Subsets Biomolecules, 2021-10-02;11(10):. 2021-10-02 [PMID: 34680079] (Human) Human
E Krepela, Z Vanickova, P Hrabal, M Zubal, B Chmielova, E Balaziova, P Vymola, I Matrasova, P Busek, A Sedo Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment International Journal of Molecular Sciences, 2021-01-21;22(3):. 2021-01-21 [PMID: 33494271] (Human) Human
AA Raha, S Chakrabort, J Henderson, E Mukaetova-, S Zaman, J Trowsdale, R Raha-Chowd Investigation of CD26, a potential SARS-CoV-2 receptor, as a biomarker of age and pathology Biosci Rep, 2020-12-23;40(12):. 2020-12-23 [PMID: 33205807] (Human) Human
LL Baggio, EM Varin, JA Koehler, X Cao, Y Lokhnygina, SR Stevens, RR Holman, DJ Drucker Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans Nat Commun, 2020-07-28;11(1):3766. 2020-07-28 [PMID: 32724076] (Human) Human
NM Varda, M Medved, L Ojsteršek The associations between some biological markers, obesity, and cardiovascular risk in Slovenian children and adolescents BMC Pediatr, 2020-02-21;20(1):81. 2020-02-21 [PMID: 32085704] (Human) Human
L De Chiara, M Páez de la, J Rodríguez-, MC Alvarez-Pa, MC Pardiñas-A, R Varela-Cal, OJ Cordero CD26-Related Serum Biomarkers: sCD26 Protein, DPP4 Activity, and Anti-CD26 Isotype Levels in a Colorectal Cancer-Screening Context Dis. Markers, 2020-01-21;2020(0):4347936. 2020-01-21 [PMID: 32051696] (Human) Human
MJ Ploquin, A Casrouge, Y Madec, N Noël, B Jacquelin, N Huot, D Duffy, SP Jochems, L Micci, C Lécuroux, F Boufassa, T Booiman, T Garcia-Tel, M Ghislain, RL Grand, O Lambotte, N Kootstra, L Meyer, C Goujard, M Paiardini, ML Albert, M Müller-Tru Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage J Int AIDS Soc, 2018-07-01;21(7):e25144. 2018-07-01 [PMID: 29987877] (Human) Human
Matrasova I, Busek P, Balaziova E, Sedo A Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2017-04-26;161(3):252-260. 2017-04-26 [PMID: 28452380] (Human) Human
Show All 12 Publications.

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Gene Symbol DPP4