Human Corin DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Corin DuoSet ELISA, 15 Plate Summary

• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CORIN

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Corin DuoSet ELISA, 15 Plate

• ATC2
• atrial natriuteric peptide-converting enzyme
• Corin
• corin, serine peptidase
• EC 3.4.21
• EC 3.4.21.-
• heart specific serine proteinase
• Heart-specific serine proteinase ATC2
• MGC119742
• pro-ANP-convertase
• Pro-ANP-Converting Enzyme
• PRSC
• serine protease
• Transmembrane protease serine 10

Background

Corin is a type II transmembrane serine protease expressed predominantly in cardiomyocytes. It converts pro-atrial natriuretic peptide (pro-ANP) to ANP.

Publications for Corin (DY2209)(7)

Publications using DY2209

• NK Binder, S Beard, N de Alwis, BR Fato, TV Nguyen, TJ Kaitu'u-Li, NJ Hannan Investigating the Effects of Atrial Natriuretic Peptide on the Maternal Endothelium to Determine Potential Implications for Preeclampsia International Journal of Molecular Sciences, 2023-03-24;24(7):. 2023-03-24 [PMID: 37047162] (Human)
• SS Zaidi, RD Ward, K Ramanathan, X Yu, IP Gladysheva, GL Reed Possible Enzymatic Downregulation of the Natriuretic Peptide System in Patients with Reduced Systolic Function and Heart Failure: A Pilot Study Biomed Res Int, 2018-07-26;2018(0):7279036. 2018-07-26 [PMID: 30148170] (Human)
• Y Gu, D Thompson, J Xu, DF Lewis, JA Morgan, DB Cooper, CE McCathran, Y Wang Aberrant pro-atrial natriuretic peptide/corin/natriuretic peptide receptor signaling is present in maternal vascular endothelium in preeclampsia Pregnancy Hypertens, 2017-12-07;11(0):1-6. 2017-12-07 [PMID: 29523263] (Human)
• B Dhole, S Gupta, SK Venugopal, A Kumar Triiodothyronine stimulates VEGF expression and secretion via steroids and HIF-1? in murine Leydig cells Syst Biol Reprod Med, 2018-02-08;0(0):1-11. 2018-02-08 [PMID: 29417848] (Human)
• C Sun, L Shen, W Sha, L Zhou, D Xu, N Dong IL-1? increases urinary corin in patients with primary proteinuric kidney diseases and in 293 cells Exp Ther Med, 2017-10-30;15(1):487-493. 2017-10-30 [PMID: 29387201] (Human)
• Zhang Y, Li H, Zhou J, Wang A, Yang J, Wang C, Liu M, Zhou T, Zhu L, Zhang Y, Dong N, Wu Q A corin variant identified in hypertensive patients that alters cytoplasmic tail and reduces cell surface expression and activity. Sci Rep, 2014-12-09;4(0):7378. 2014-12-09 [PMID: 25488193] (Human)
• Ibebuogu UN, Gladysheva IP, Houng AK Decompensated heart failure is associated with reduced corin levels and decreased cleavage of pro-atrial natriuretic peptide. Circ Heart Fail, 2011-01-07;4(2):114-20. 2011-01-07 [PMID: 21216831] (Human)

Bioinformatics

• Gene Symbol: CORIN