HISPPD1 Antibody [Janelia Fluor® 669]

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 669

HISPPD1 Antibody [Janelia Fluor® 669] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 925 to 975 of human Diphosphoinositol Pentakisphosphate Kinase 2 using the numbering given in entry BAA24863.2 (GeneID 23262).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPIP5K2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HISPPD1 Antibody [Janelia Fluor® 669]

• diphosphoinositol pentakisphosphate kinase 2FLJ21506
• EC 2.7.4.21
• EC 2.7.4.24
• HISPPD1histidine acid phosphatase domain containing 1
• Histidine acid phosphatase domain-containing protein 1
• hsVIP2
• inositol heptaphosphate kinase 2
• inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
• InsP6 and PP-IP5 kinase 2
• KIAA0433FLJ23463
• VIP1 homolog 2
• VIP2IP7K2

Background

Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 (PubMed 17690096)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPIP5K2