HECTD1 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 650

HECTD1 Antibody [DyLight 650] Summary

• Immunogen: The immunogen for this product maps to a region between residue 2100 and 2150 of human HECT Domain Containing 1 using the numbering given in entry AAP13073.1 (GeneID 25831).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HECTD1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HECTD1 Antibody [DyLight 650]

• E3 ligase for inhibin receptor
• E3 ubiquitin-protein ligase HECTD1
• EC 6.3.2.-
• EULIR
• HECT domain containing 1
• HECT domain-containing protein 1
• KIAA1131FLJ38315

Background

The HECTD1 gene encodes a2, 610 amino acid long, 298 kDA E3 ubiquitin-protein ligase HECTD1 protein that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester. It then directly transmits the ubiquitin to targeted substrates and may be essential for development of the head mesenchyme and neural tube closure. HECTD1 interacts in interferon signaling and cytokine signaling in the immune system and is known to interact with various genes such as NME2, ERCC2, PITX2, CCNA2, and NME1-NME2. HECTD1 has been investigated in many diseases such as angelman syndrome, teratoma, carcinoma, malaria, and influenza.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HECTD1