Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: IP, WB (-)
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The HECTD1 gene encodes a2, 610 amino acid long, 298 kDA E3 ubiquitin-protein ligase HECTD1 protein that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester. It then directly transmits the ubiquitin to targeted substrates and may be essential for development of the head mesenchyme and neural tube closure. HECTD1 interacts in interferon signaling and cytokine signaling in the immune system and is known to interact with various genes such as NME2, ERCC2, PITX2, CCNA2, and NME1-NME2. HECTD1 has been investigated in many diseases such as angelman syndrome, teratoma, carcinoma, malaria, and influenza.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
25831 |
| Alternate Names |
- E3 ligase for inhibin receptor
- E3 ubiquitin-protein ligase HECTD1
- EC 6.3.2.-
- EULIR
- HECT domain containing 1
- HECT domain-containing protein 1
- KIAA1131FLJ38315
|
