GPRC5B Antibody (575926) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 575926
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

GPRC5B Antibody (575926) [Janelia Fluor® 525] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: NS0 mouse myeloma cell line transfected with human GPRC5B
  Accession # Q9NZH0
• Specificity: Detects human GPRC5B.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB10253. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GPRC5B Antibody (575926) [Janelia Fluor® 525]

• G protein-coupled receptor, family C, group 1, member B
• G protein-coupled receptor, family C, group 5, member B
• GPRC5B
• RAIG2
• RAIG-2A-69G12.1
• RAIG2G-protein coupled receptor family C group 5 member B
• retinoic acid responsive gene protein
• Retinoic acid-induced gene 2 protein

Background

GPRC5B is an Orphan-C GPCR induced by retinoids. GPRC5B shows some homologies to the metabotropic glutamate receptor-like family of GPCRs; however, the GPRC5B protein has a short N-terminal domain compared to other family C members. GPRC5B expression is reported to be widespread with highest levels observed in brain, kidney, pancreas and testis. ESTs have been isolated from a wide variety of human tissue libraries, including normal adrenal, brain, heart/melanocyte/uterus and pineal, and cancerous germ cell, nerve, ovary and parathyroid.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.