Glycophorin C Antibody (BRIC100)

Product Discontinued

Glycophorin C Antibody (BRIC100) Summary

• Immunogen: Synthetic peptide corresponding to amino acids in the cytoplasmic domain of GPC
• Specificity: Recognizes a 17 amino acid residue within the cytoplasmic domain of glycophorin C (GPC), which has recently been designated CD236.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GYPC
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Tris-Glycine (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for Glycophorin C Antibody (BRIC100)

• CD236 antigen
• CD236
• CD236R
• GE
• GLPC
• glycoconnectin
• glycophorin C (Gerbich blood group)
• glycophorin-C
• glycophorin-D
• Glycoprotein beta
• GPCMGC126191
• GPD
• GYPD
• MGC117309
• MGC126192
• PAS-2
• PAS-2'
• Sialoglycoprotein D

Background

CD236 is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. CD236 (Glycophorin C) plays an important role in regulating the stability of red cells. Expression of Glycophorin C is not restricted to erythroid cells but is broadly distributed in both erythroid and non erythroid tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GYPC
• Entrez:
  • 2995(Human)
• Uniprot:
  • P04921(Human)