Recombinant Human Glutathione Peroxidase 3/GPX3 FLAG Protein

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human Glutathione Peroxidase 3/GPX3 FLAG Protein Summary

• Description: Human Glutathione Peroxidase 3/GPX3 (aa 21-226) fused at the N-terminus to a FLAG(R)-tag.
  
  Source: HEK 293 cells

  Uniprot ID: P22352

• Source: HEK293
• Protein/Peptide Type: Recombinant Protein
• Gene: GPX3
• Purity: >90% SDS-PAGE
• Endotoxin Note: <0.1EU/ug purified protein (LAL test; Lonza).

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 30 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.2
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90% SDS-PAGE

Alternate Names for Recombinant Human Glutathione Peroxidase 3/GPX3 FLAG Protein

• EC 1.11.1
• EC 1.11.1.9
• Extracellular glutathione peroxidase
• glutathione peroxidase 3 (plasma)
• Glutathione Peroxidase 3
• GPX3
• GPx-3
• GPXP
• GPX-P
• GSHPx-3
• GSHPx-P
• Plasma glutathione peroxidase

Background

Glutathione Peroxidase 3 (GPX3) belongs to the glutathione peroxidase family. It protects cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide by glutathione. There is increasing evidence that GPX3 is a novel tumor suppressor and a therapeutic target for insulin resistance and diabetes mellitus.

GPX-3 antibodies are useful tools for research on cellular response to oxidative stress as well as cancer and diabetes studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GPX3
• Uniprot:
  • P22352(Human)