gamma-Synuclein Antibody (2C3)

Product Discontinued

gamma-Synuclein Antibody (2C3) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: SNCG (AAH14098, 21 a.a. - 127 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD
• Specificity: SNCG - synuclein, gamma (breast cancer-specific protein 1)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SNCG
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 26563826).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for gamma-Synuclein Antibody (2C3)

• BCSG1
• BCSG1PERSYN
• Breast cancer-specific gene 1 protein
• gamma-Synuclein
• persyn
• PRSN
• SNCG
• SRPRSN
• Synoretin
• synuclein, gamma (breast cancer-specific protein 1)
• Synuclein-gamma

Background

Synuclein-gamma is a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for gamma-Synuclein Antibody (H00006623-M01)(2)

Publications using H00006623-M01

• Sluch VM, Davis CH, Ranganathan V et al. Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line. Sci Rep 2015-01-01 [PMID: 26563826] (ICC/IF, Human)
• Gramlich OW, Ding QJ, Zhu W et al. Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients. Acta Neuropathol Commun. 2015-09-15 [PMID: 26374513]

Bioinformatics

• Gene Symbol: SNCG
• Entrez:
  • 6623(Human)
• OMIM:
  • 602998(Human)
• Uniprot:
  • AAH14098(Human)