FUS2 Antibody

Product Discontinued

FUS2 Antibody Summary

• Immunogen: Synthetic peptide: VRGRPIFWMEKDI, represening the C-Terminus of the human protein (residues 274-286), according to NP_036323.
• Localization: Cytoplasmic
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NAA80
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Peptide ELISA 1:8000
• Application Notes: Western Blot: No signal obtained yet but low background observed in HepG2 and human heart lysates at up to 1ug/ml.
• Control:

  FUS2 Overexpression Lysate

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for FUS2 Antibody

• FUS-2
• FUS2EC 2.3.1.-
• N-acetyltransferase 6 (GCN5-related)
• N-acetyltransferase 6
• Protein fus-2
• Protein fusion-2

Background

Vertebrate FUS2 genes, which are known to be putative tumor suppressor gene, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain is essential enzymes involved in several sophisticated cellular processes such as N-acetylation, O-acetylatin. NAT enzymes may be involved in susceptibility to cancer including colorectal cancer because of the presence of carcinogenic heterocyclic amines in some cooked foods. FUS2 was physically localized to the cytoplasm. Also, FUS2 showed the actin dependent movement, closely related to the polarization in the budding yeast, Saccharomyces cerevisiae.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NAA80
• Entrez:
  • 24142(Human)
• Uniprot:
  • NP_036323.(Human)