FRAS1 (Fraser syndrome 1) Antibody

Images

 
Western Blot: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cell lysate with FRAS1 antibody at (A) 0.5 and (B) 1ug/mL.
Immunocytochemistry/ Immunofluorescence: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - FRAS1 (Fraser syndrome 1) Antibody A-20 cells with FRAS1 antibody at 20 ug/mL.
Immunofluorescence: FRAS1 (Fraser syndrome 1) Antibody [NBP1-77181] - A20 cells at 20 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

FRAS1 (Fraser syndrome 1) Antibody Summary

Immunogen
Antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2. The immunogen is located within amino acids 1920 - 1970 of FREM2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FRAS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunofluorescence 20 ug/mL
Control Peptide
FRAS1 (Fraser syndrome 1) Peptide (NBP1-77181PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FRAS1 (Fraser syndrome 1) Antibody

  • DKFZp686I05113
  • extracellular matrix protein FRAS1
  • FLJ14927
  • FLJ22031
  • Fraser syndrome 1
  • KIAA1500DKFZp686P08111

Background

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FRAS1
Uniprot