Factor IX Antibody

Western Blot: Factor IX Antibody [H00002158-A01] - Detection against Immunogen (36.56 KDa) .

Product Discontinued

Factor IX Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: F9 (NP_000124, 96 a.a. - 190 a.a.) partial recombinant protein with GST tag. QCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLT
• Specificity: F9 - coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: F9
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50 % glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Factor IX Antibody

• Christmas Factor
• Coagulation Factor IX
• EC 3.4.21
• EC 3.4.21.22
• F9
• factor 9
• FIX
• HEMB
• MGC129641
• MGC129642
• P19
• Plasma Thromboplastic Component
• Plasma thromboplastin component
• PTC
• THPH8

Background

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: F9
• Entrez:
  • 2158(Human)
• OMIM:
  • 306900(Human)
• Uniprot:
  • NP_000124(Human)