Ext2 Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, CaSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated

Order Details

Ext2 Antibody Summary

Immunogen
Peptide with sequence C-PLKVVEHRADPVL corresponding to C-Terminus according to NP_997005.1.
Epitope
C-PLKVVEHRADPVL
Specificity
This antibody is expected to recognize isoform 1 and 2 (NP_000392.2; NP_997005.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
EXT2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Preliminary experiments in lysates of HEK293 gave no specific signal but low background.
Publications
Read Publication using NBP1-52137.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Ext2 Antibody

  • EC 2.4.1.224
  • EC 2.4.1.225
  • exostoses (multiple) 2
  • Exostosin 2
  • exostosin-2
  • EXT2
  • Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase
  • Multiple Exostoses Protein 2
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
  • Putative tumor suppressor protein EXT2
  • SOTV

Background

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Ext2 Antibody (NBP1-52137)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EXT2
Entrez
Uniprot