EPC1 Antibody

Images

 
Western Blot: EPC1 Antibody [NBP1-71865] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-EPC1 antibody used for WB at 0.1 mcg/ml (A) and 1 ...read more
Proximity Ligation Assay: EPC1 Antibody [NBP1-71865] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (NB100-271) and rabbit anti-human EPC1 (NBP1-71865). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: EPC1 Antibody [NBP1-71865] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human DMAP1 (NB100-256) and rabbit anti-human EPC1 (NBP1-71865). Image merged from DAPI (2ms) and Texas ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, PLA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml
 

Independent Antibodies

       

Order Details

EPC1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 325 and 375 of human Enhancer of Polycomb 1 using the numbering given in entry NP_079485.1 (GeneID 80314).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EPC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-10 mcg/mg
  • Proximity Ligation Assay 1:1000-1:20000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EPC1 Antibody

  • DKFZp781P2312
  • enhancer of polycomb 1
  • enhancer of polycomb homolog 1 (Drosophila)
  • enhancer of polycomb homolog 1
  • Epl1

Background

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for EPC1 Antibody (NBP1-71865)

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Bioinformatics

Gene Symbol EPC1
Uniprot