EFCAB4B Antibody - BSA Free

Images

 
Western Blot: EFCAB4B Antibody [NBP1-76493] - mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/mL.
Immunohistochemistry: EFCAB4B Antibody - BSA Free [NBP1-76493] - Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 u/mL.
Immunocytochemistry/ Immunofluorescence: EFCAB4B Antibody - BSA Free [NBP1-76493] - Immunofluorescence of EFCAB4B in human kidney tissue with EFCAB4B antibody at 20 u/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

EFCAB4B Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit EFCAB4B Antibody - BSA Free (NBP1-76493) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B. The immunogen is located within amino acids 640 - 690 of EFCAB4B. Amino Acid Squence: KLDNEKEREVPRGL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRACR2A
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 1 ug/ml
Control Peptide
EFCAB4B Peptide (NBP1-76493PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for EFCAB4B Antibody - BSA Free

  • Calcium release-activated calcium channel regulator 2A
  • CRAC channel regulator 2A
  • CRACR2A
  • DKFZp686G13246
  • EF-hand calcium binding domain 4B
  • EF-hand calcium-binding domain-containing protein 4B
  • FLJ33046
  • FLJ33805
  • MGC4266

Background

EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CRACR2A
Uniprot