EDAR Antibody (6C12)

Western Blot: EDAR Antibody (6C12) [H00010913-M01] - EDAR monoclonal antibody (M01), clone 6C12. Analysis of EDAR expression in human kidney.

Product Discontinued

EDAR Antibody (6C12) Summary

• Immunogen: EDAR (NP_071731, 64 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKEL
• Specificity: EDAR - ectodysplasin A receptor
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: EDAR
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for EDAR Antibody (6C12)

• Anhidrotic ectodysplasin receptor 1
• DLED3
• Ectodermal dysplasia receptor
• ectodysplasin 1, anhidrotic receptor
• ectodysplasin A receptor
• Ectodysplasin-A receptor
• ED1R
• ED5
• EDA1R
• EDA3EDA-A1 receptor
• EDA-A1R
• EDAR
• FLJ94390
• HRM1
• mouse, homolog of
• tumor necrosis factor receptor superfamily member EDAR

Background

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EDAR
• Entrez:
  • 10913(Human)
• OMIM:
  • 129(Human)
• Uniprot:
  • NP_071731()