EBI2/GPR183 Antibody (486617) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 486617
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

EBI2/GPR183 Antibody (486617) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human EBI2 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for EBI2/GPR183 Antibody (486617) [Alexa Fluor™ Plus 555]

• EBI2
• EBI2Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupledreceptor)
• EBV-induced G-protein coupled receptor 2
• Epstein-Barr virus-induced G-protein coupled receptor 2
• G protein-coupled receptor 183
• GPR183
• G-protein coupled receptor 183

Background

Epstein-Barr virus-induced G-protein coupled receptor 2, also known as EBI2 or GPR183 is a G-protein coupled receptor (GPCR) expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, and monocytes/macrophages. The GPR183 gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of the Burkitt's lymphoma cell line BL41. GPR183 collaborates with CXCR5 to mediate B cell homing within a lymph node, probably by forming a heterodimer with CXCR5 that affects its interaction with CXCL13

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.