DZIP3 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 650

DZIP3 Antibody [DyLight 650] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human DZIP3 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DZIP3
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DZIP3 Antibody [DyLight 650]

• DAZ interacting protein 3, zinc finger
• DAZ-interacting protein 3
• E3 ubiquitin-protein ligase DZIP3
• EC 6.3.2.-
• FLJ13327
• FLJ57977
• FLJ58022
• FLJ58223
• hRUL138KIAA0675
• human RNA-binding ubiquitin ligase of 138 kDa
• RNA-binding ubiquitin ligase of 138 kDa
• UURF2 ubiquitin ligase
• UURF2
• zinc finger DAZ interacting protein 3

Background

The DZIP3 gene codes a E3 ubiquitin-protein ligase DZIP3 protein that in one isoform is 1,208 amino acids long and 138 kDA and in the other is 303 amino acids long at 35 kDA. These proteins are able to specifically bind RNA as well as control ubiquitination and proteasomal degradation of target proteins by receiving ubiquitin from an E2 ubiquitin-conjugating enzyme (in the form of a thioester) then transfers the material to targeted substrates. DZIP3 is active in adaptive immune system, protein modification, and antigen processing (specifically ubiquitination and proteasome degradation as described above). DZIP3 has been researched in various diseases such as azoospermia and ataxia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DZIP3