DZIP3 Products

Description

The DZIP3 gene codes a E3 ubiquitin-protein ligase DZIP3 protein that in one isoform is 1,208 amino acids long and 138 kDA and in the other is 303 amino acids long at 35 kDA. These proteins are able to specifically bind RNA as well as control ubiquitination and proteasomal degradation of target proteins by receiving ubiquitin from an E2 ubiquitin-conjugating enzyme (in the form of a thioester) then transfers the material to targeted substrates. DZIP3 is active in adaptive immune system, protein modification, and antigen processing (specifically ubiquitination and proteasome degradation as described above). DZIP3 has been researched in various diseases such as azoospermia and ataxia.

Bioinformatics

Entrez	9666 Human
Uniprot	NM_014648 Human NP_055463 Human Q86Y13 Human
Product By Gene ID	9666
Alternate Names	DAZ interacting protein 3, zinc finger DAZ-interacting protein 3 E3 ubiquitin-protein ligase DZIP3 EC 6.3.2.- FLJ13327 FLJ57977 FLJ58022 FLJ58223 hRUL138KIAA0675 human RNA-binding ubiquitin ligase of 138 kDa RNA-binding ubiquitin ligase of 138 kDa UURF2 ubiquitin ligase UURF2 zinc finger DAZ interacting protein 3

Research Areas for DZIP3

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Zinc Finger