DUSP18 Antibody

Western Blot: DUSP18 Antibody [NB100-56481] - Analysis of DUSP18 in rat testis lysate in the 1) absence and 2) presence of immunizing peptide and in human testis lysate in the 3) absence and 4) presence of immunizing peptide using this antibody at 0.5 ug/ml.

Product Discontinued

DUSP18 Antibody Summary

• Immunogen: A portion of amino acids 1-50 of human DUSP18 was used as the immunogen.
• Predicted Species: Canine (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DUSP18
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-2 ug/ml
• Control:

  Human Testis Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Sequence identity: 85% with rat proteins

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS containing 0.2% gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein G purified

Alternate Names for DUSP18 Antibody

• bK963H5.1
• DSP18
• dual specificity phosphatase 18
• dual specificity protein phosphatase 18
• DUSP20
• EC 3.1.3.16
• EC 3.1.3.48
• LMWDSP20
• LMW-DSP20
• Low molecular weight dual specificity phosphatase 20
• MGC32658

Background

DUSP18 (E.C 3.1.3.16), a novel DSP, is a member of highly conserved protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation and mitogenic signal transduction. DUSP18 is a low molecular weight protein consisting of conserved N-terminal DSP domain but lacks CH2 domain. Studies reveal that DUSP18 is a unique DSP that interacts and dephosphorylates SAPK/JNK. Reports suggest it inhibits SAPK/JNK in vivo and might serve an important role in the regulation of SAPK/JNK pathway. Northern Blot analysis detected a ubiquitous expression of DUSP18.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DUSP18
• Entrez:
  • 150290(Human)
• Uniprot:
  • Q8NEJ0(Human)