DUSP18 Antibody

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Western Blot: DUSP18 Antibody [NB100-56481] - Analysis of DUSP18 in rat testis lysate in the 1) absence and 2) presence of immunizing peptide and in human testis lysate in the 3) absence and 4) presence of immunizing ...read more

Product Details

Summary
Reactivity Hu, Bv, Pm, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

DUSP18 Antibody Summary

Immunogen
A portion of amino acids 1-50 of human DUSP18 was used as the immunogen.
Predicted Species
Canine (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DUSP18
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.5-2 ug/ml
Control
Human Testis Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

Sequence identity: 85% with rat proteins

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein G purified

Alternate Names for DUSP18 Antibody

  • bK963H5.1
  • DSP18
  • dual specificity phosphatase 18
  • dual specificity protein phosphatase 18
  • DUSP20
  • EC 3.1.3.16
  • EC 3.1.3.48
  • LMWDSP20
  • LMW-DSP20
  • Low molecular weight dual specificity phosphatase 20
  • MGC32658

Background

DUSP18 (E.C 3.1.3.16), a novel DSP, is a member of highly conserved protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation and mitogenic signal transduction. DUSP18 is a low molecular weight protein consisting of conserved N-terminal DSP domain but lacks CH2 domain. Studies reveal that DUSP18 is a unique DSP that interacts and dephosphorylates SAPK/JNK. Reports suggest it inhibits SAPK/JNK in vivo and might serve an important role in the regulation of SAPK/JNK pathway. Northern Blot analysis detected a ubiquitous expression of DUSP18.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DUSP18
Entrez
Uniprot