DPPIV/CD26 Antibody (202.36)

Product Discontinued

DPPIV/CD26 Antibody (202.36) Summary

• Immunogen: The antibody reacts with the CD26 antigen.
• Specificity: 202.36 reacts with human CD26 (Dipeptidyl peptidase IV), a 110 kD protein which occurs in the cell membrane of T lymphocyte and is upregulated after activation. CD26 is also present on endothelial cells. The mAb was clustered at the VI WLDA. Source: A BALB/c mouse was immunized with a T cell clone. Splenocytes were fused with mouse myeloma NS1 cells.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DPP4
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunoprecipitation 1:10-1:500
• Application Notes: 202.36 has been tested in flow cytometry and in immuno precipitation against CD26.

Reactivity Notes

Human,Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 0.1 mg/ml PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for DPPIV/CD26 Antibody (202.36)

• ADABP
• ADCP-2
• ADCP2DPP IV
• Adenosine deaminase complexing protein 2TP103
• CD26 antigen
• CD26
• CD26T-cell activation antigen CD26
• dipeptidyl peptidase 4
• Dipeptidyl peptidase IV
• dipeptidylpeptidase 4
• dipeptidyl-peptidase 4
• dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
• DPP4
• DPPIV
• EC 3.4.14.5

Background

CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DPP4