Doc2-alpha Antibody

Product Discontinued

Doc2-alpha Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: DOC2A (AAH63436, 1 a.a. - 400 a.a.) full-length recombinant protein with GST tag. MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLALAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
• Specificity: DOC2A - double C2-like domains, alpha
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: DOC2A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Doc2-alpha Antibody

• Doc2 alpha
• Doc2
• DOC2A
• doc2-alpha
• double C2-like domain-containing protein alpha
• double C2-like domains, alpha

Background

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Doc2-alpha Antibody (H00008448-A01)(1)

Publication using H00008448-A01

• Yao J, Gaffaney JD, Kwon SE, Chapman ER. Doc2 is a ca(2+) sensor required for asynchronous neurotransmitter release. Cell. 2011-10-28 [PMID: 22036572]

Bioinformatics

• Gene Symbol: DOC2A
• Entrez:
  • 8448(Human)
• OMIM:
  • 604567(Human)
• Uniprot:
  • AAH63436(Human)