DMRT2 Antibody (PCRP-DMRT2-1B11) [Janelia Fluor® 585]

Product Discontinued

DMRT2 Antibody (PCRP-DMRT2-1B11) [Janelia Fluor® 585] Summary

• Immunogen: Recombinant full-length human DMRT2 protein (Uniprot: Q9Y5R5)
• Localization: Nucleus
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DMRT2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Protein Array
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DMRT2 Antibody (PCRP-DMRT2-1B11) [Janelia Fluor® 585]

• doublesex and mab-3 related transcription factor 2
• doublesex- and mab-3-related transcription factor 2
• Doublesex-like 2 protein
• DSXL2
• DSXL-2
• terra-like protein

Background

DMRT2, also known as Doublesex and mab-3-related transcription factor 2, consists of a 61.8 kDa, a 24.5 kDa, and a 36.9 kDa isoform and is involved in regulating activation of the gene MYF5 as a transcription factor during embryogenesis and somite development. Current research has linked the protein to diseases such as sex reversal, attention deficit hyperactivity disorder, leukemia, anemia, and gonadal dysgenesis. The protein interacts with UBC, CCDC18, BCLAF1, RPS3, and MYBBP1A in transcription pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DMRT2