DIAPH3 Antibody

Product Discontinued

DIAPH3 Antibody Summary

• Immunogen: DIAPH3 (NP_112194, 632 a.a. ~ 730 a.a) partial recombinant protein with GST tag.PDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETFPPPEDLHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYYAIDVKKV
• Specificity: DIAPH3 - diaphanous homolog 3 (Drosophila)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: DIAPH3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DIAPH3 Antibody

• DIAP3
• diaphanous homolog 3 (Drosophila)
• diaphanous-related formin 3
• DKFZp434C0931
• DKFZp686A13178
• homolog) 3
• mDia2
• protein diaphanous homolog 3

Background

DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to themembrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, andtranscriptional activation of the serum r

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DIAPH3 Antibody (H00081624-A01)(1)

Publication using H00081624-A01

• Kyrkou A, Soufi M, Bahtz R et al. RhoD participates in the regulation of cell-cycle progression and centrosome duplication. Oncogene. 2013-04-04 [PMID: 22665057]

Bioinformatics

• Gene Symbol: DIAPH3
• Entrez:
  • 81624(Human)
• Uniprot:
  • NP_112194(Human)