delta Opioid R/OPRD1 Antibody

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Immunohistochemistry-Paraffin: delta Opioid R/OPRD1 Antibody [NLS225] - Brain, Neurons and Glia

Product Details

Summary
Reactivity Hu, Pm, PmSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

delta Opioid R/OPRD1 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from C-terminus of human Delta Opioid Receptor.
Specificity
Human Delta Opioid Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ZC3H11A (44%).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPRD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 32 ug/ml
Control
delta Opioid R/OPRD1 Overexpression Lysate

Reactivity Notes

Gorilla, Marmoset. Predicted cross-reactivity based on sequence identity: Canine (88%), Elephant (88%), Panda (88%), Mouse (81%), Bat (81%), Bovine (81%), Rabbit (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for delta Opioid R/OPRD1 Antibody

  • delta Opioid R
  • delta opioid receptor 1
  • delta-type opioid receptor
  • DOP
  • dOpioidR
  • DOR1
  • D-OR-1
  • DOR-1
  • OP1
  • opioid receptor, delta 1
  • OPRD
  • OPRD1

Background

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NLS225
Species: Hu, Pm, Pm
Applications: IHC, IHC-P

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics

Gene Symbol OPRD1
Entrez