Cytosolic Sulfotransferase 1C2/SULT1C2 Antibody (844529) [Alexa Fluor® 532]

• Applications: WB, IHC
• Clone: 844529
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Cytosolic Sulfotransferase 1C2/SULT1C2 Antibody (844529) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 1C2/SULT1C2
  Ala2-Leu296
  Accession # O00338
• Specificity: Detects human Cytosolic Sulfotransferase 1C2/SULT1C2 in ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Cytosolic sulfotransferases catalyze the sulfonation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are distinct from Golgi-resident sulfotransferases by the absence of transmembrane domains and are located in the cytoplasm (1, 2). SULT1C2 is mainly expressed in the gastrointestinal tract (stomach, duodenum, jejunum, ileum, colon, caecum and rectum), liver and kidneys, but not in the lungs (3). In contrast, SULT1C4, a sulfotransferase that is most closely related to SULT1C2 (4), is expressed at higher levels in fetal lung and kidney and at lower levels in fetal heart. So far, SULT1C2 is found to be active only on p-nitrophenol (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.