CRLR Antibody (998820) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 998820
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

CRLR Antibody (998820) [Alexa Fluor® 405] Summary

• Immunogen: Synthetic peptide containing human CALCRL
  Accession # Q16602
• Specificity: Detects human CALCRL in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CRLR Antibody (998820) [Alexa Fluor® 405]

• calcitonin gene-related peptide type 1 receptor
• calcitonin receptor-like
• CALCRL
• CGRP type 1 receptor
• CGRPR
• CGRPRCRLRCalcitonin receptor-like receptor
• CRLR

Background

The calcitonin receptor-like receptor (CRLR), a class B GPCR, forms a heterodimer with receptor activity-modifying protein 2 (RAMP2), and serves as the adrenomedullin (AM) receptor to control neovascularization, while CRLR and RAMP1 form the calcitonin gene-related peptide (CGRP) receptor. CALCRL is pharmacologically identical to CGRP receptor-1, a putative molecular target of CGRP and adrenomedullin. CALCRL is predominantly expressed in the lung and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.