Recombinant Human COPS8 Protein

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SDS-Page: Recombinant Human COPS8 Protein [NBP1-72515] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human COPS8 Protein Summary

Description
A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-209 of Human COPS8

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MPVAVMAESA FSFKKLLDQC ENQELEAPGG IATPPVYGQL LALYLLHNDM NNARYLWKRI PPAIKSANSE LGGIWSVGQR IWQRDFPGIY TTINAHQWSE TVQPIMEALR DATRRRAFAL VSQAYTSIIA DDFAAFVGLP VEEAVKGILE QGWQADSTTR MVLPRKPVAG ALDVSFNKFI PLSEPAPVPP IPNEQQLARL TDYVAFLEN

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
COPS8
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
25.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human COPS8 Protein

  • COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
  • COP9 homolog
  • COP9 signalosome complex subunit 8
  • COP9
  • CSN8JAB1-containing signalosome subunit 8
  • hCOP9
  • MGC1297
  • MMMEP
  • SGN8MGC43256
  • Signalosome subunit 8

Background

COP9 signalosome complex subunit 8 isoform 1, also known as COPS8, is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Recombinant human COPS8 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol COPS8