CoCoA Antibody [HRP]

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Product Details

Summary
Product Discontinued
View other related CoCoA Primary Antibodies

Order Details


    • Catalog Number
      NBP2-97283H
    • Availability
      Product Discontinued

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CoCoA Antibody [HRP] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human CoCoA fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CALCOCO1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen Affinity-purified

Alternate Names for CoCoA Antibody [HRP]

  • calcium binding and coiled-coil domain 1
  • calphoglin
  • Cocoa
  • Coiled-coil coactivator protein
  • coiled-coil leucine zipper coactivator 1
  • inorganic pyrophosphatase activator
  • KIAA1536calcium-binding and coiled-coil domain-containing protein 1
  • Sarcoma antigen NY-SAR-3

Background

HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional CoCoA Products

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Bioinformatics

Gene Symbol CALCOCO1