CD79A Antibody (ZL7-4) [FITC]

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Flow Cytometry: CD79A Antibody (ZL7-4) [FITC] [NB100-64015] - Staining of RAMOS cells with MOUSE ANTI HUMAN CD79a:FITC

Product Details

Summary
Product Discontinued
View other related CD79A Primary Antibodies

Order Details


    • Catalog Number
      NB100-64015
    • Availability
      Product Discontinued

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CD79A Antibody (ZL7-4) [FITC] Summary

Immunogen
Daudi IgM complex.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD79A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
This antibody is useful for Immunoprecipitation, Flow cytometry / FACS analysis, Immunohistochemistry-Frozen
Positive Control
CD79A Lysate (NBL1-08969)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline, 1% Bovine Serum Albumin.
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for CD79A Antibody (ZL7-4) [FITC]

  • CD79A antigen (immunoglobulin-associated alpha)
  • CD79a antigen
  • CD79a molecule, immunoglobulin-associated alpha
  • CD79A
  • IGAB-cell antigen receptor complex-associated protein alpha chain
  • ig-alpha
  • MB-1 membrane glycoprotein
  • MB1
  • MB-1
  • Membrane-bound immunoglobulin-associated protein
  • Surface IgM-associated protein

Background

A disulphide linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Research Areas for CD79A Antibody (NB100-64015)

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Blogs on CD79A.

CD79b - A Signal Transduction Component of the B-cell Receptor
The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...  Read full blog post.

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Bioinformatics

Gene Symbol CD79A
Entrez