CD39L1/ENTPD2 Antibody [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 647

CD39L1/ENTPD2 Antibody [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human CD39L1 in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse CD39L1 and less than 1% cross-reactivity with recombinant human (rh) CD39L2, rhCD39L3, and rhCD39L4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD39L1/ENTPD2 Antibody [Alexa Fluor™ Plus 647]

• CD39 antigen-like 1
• CD39L1
• CD39L1NTPDase 2
• CD39-like-1
• EC 3.6.1
• EC 3.6.1.-
• EC 3.6.1.5
• Ecto-ATP diphosphohydrolase 2
• Ecto-ATPase 2
• Ecto-ATPase
• Ecto-ATPDase 2
• ectonucleoside triphosphate diphosphohydrolase 2
• ENTPD2
• NTPD2
• NTPDase 2
• NTPDase-2

Background

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells (1). CD39L1 is a Ca²⁺ and Mg²⁺ dependent enzyme that activates platelets by preferentially converting ATP to ADP (2). CD39L1 plays a role in regulating thrombosis and inflammation (3). It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation (2, 4).

1. Zimmermann, H. et al. 2000 Proceedings of the Second International Workshop on EctoATPases and Related Ectonucleotidases:18.
2. Robson, S.C. et al. 2001 Drug Dev. Res. 53:193.
3. Marcus, A.J. et al. 2005 Semin. Thromb. Hemost. 31:234.
4. Sevigny, J. et al. 2002 Blood 99:2801.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.