CaMKIIN2 [p Thr286] Antibody

Images

 
Western Blot: CaMKIIN2 [p Thr286] Antibody [NBP1-50259] - Analysis of rat brain lysate, showing specific immunolabeling of the ~50k a- and the ~60k b-CaM Kinase II phosphorylated at Thr286 (Control). The ...read more
Immunohistochemistry-Paraffin: CaMKIIN2 [p Thr286] Antibody [NBP1-50259] - Analysis of anti-CAMK2 antibody with human brain, cortex at dilution 1:200.
Immunohistochemistry-Paraffin: CaMKIIN2 [p Thr286] Antibody [NBP1-50259] - Analysis of anti-CAMK2 antibody with human spleen.

Product Details

Summary
Reactivity Hu, Mu, Rt, XpSpecies Glossary
Applications WB, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

CaMKIIN2 [p Thr286] Antibody Summary

Immunogen
Phosphopeptide corresponding to amino acid residues surrounding the phosphoThr286 found in rat brain CaM Kinase II.
Modification
p Thr286
Specificity
Specific for the ~50k a-CaM Kinase II and the ~60k R-CaM Kinase II proteins phosphorylated at Thr286. Immunolabeling is blocked by the X-phosphatase treatment
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CAMK2N2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunohistochemistry-Paraffin 1:200

Reactivity Notes

Rat, Xenopus, Human, Mouse

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for CaMKIIN2 [p Thr286] Antibody

  • calcium/calmodulin-dependent protein kinase II inhibitor 2
  • CaM-KII inhibitory protein
  • CAMKIIN
  • CaM-KIIN

Background

This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CAMK2N2