CaM Kinase II gamma Antibody

Product Discontinued

CaM Kinase II gamma Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CaMKII gamma. The exact sequence is proprietary.
• Predicted Species: Rat (100%), Porcine (100%), Bovine (100%), Rabbit (100%), Rhesus Macaque (100%), Xenopus (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAMK2G
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000
• Application Notes: Use in Immunohistochemistry-paraffin reported in scientific literature (PMID: 28972541).
• Theoretical MW: 63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (97%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for CaM Kinase II gamma Antibody

• calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
• calcium/calmodulin-dependent protein kinase II gamma
• calcium/calmodulin-dependent protein kinase type II subunit gamma
• CaM Kinase II gamma
• CaM kinase II subunit gamma
• CAMK
• CAMK2G
• CAMKG
• CAMKGFLJ16043
• CaMK-II subunit gamma
• CAMK-II
• EC 2.7.11
• EC 2.7.11.17
• MGC26678

Background

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for CaM Kinase II gamma Antibody (NBP2-15685)(3)

Publications using NBP2-15685

• Huang X, Liu C, Kong N et al. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages Nature protocols 2022-02-04 [PMID: 35121853]
• Tao W, Yurdagul A, Kong N et al. siRNA nanoparticles targeting CaMKII gamma in lesional macrophages improve atherosclerotic plaque stability in mice Sci Transl Med 2020-07-22 [PMID: 32718990]
• Doran AC, Ozcan L, Cai B et al. CAMKIIg suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J. Clin. Invest. 2017-11-01 [PMID: 28972541] (IHC-P, Mouse)

Bioinformatics

• Gene Symbol: CAMK2G
• Uniprot:
  • Q13555(Human)