CaM Kinase II Antibody (990714) [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC, ICC/IF
• Clone: 990714
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

CaM Kinase II Antibody (990714) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human CaM Kinase II γ
  Ala448-Gln558
  Accession # Q13555
• Specificity: Detects human CaM Kinase II gamma in direct ELISAs. Detects human CaM Kinase II alpha , beta , gamma , and δ in Western blots. Detects human, mouse, and rat CaM Kinase II in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CaM Kinase II Antibody (990714) [Alexa Fluor® 488]

• Calcium/calmodulin-dependent protein kinase;Calcium/calmodulin-dependent protein kinase type II subunit beta;CAM2;CAMK2;CAMK2B;CAMKB;CaMKIIbeta;MRD54
• CaM Kinase II
• CAMK2
• CAMK2B

Background

Calcium/calmodulin-dependent protein kinase type II gamma (CaMKII gamma ) belongs to a family of multifunctional serine/threonine kinases activated in response to increases in intracellular calcium. There are 4 CaMKII isozymes, alpha , beta , gamma , and δ, and each can yield several isoforms through alternative splicing. CaMKII isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. The widely expressed CaMKII gamma from human, mouse, and rat share 100% aa sequence identity within aa 448-558 of isoform 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.