Recombinant Human Calcineurin B Protein

Images

 
SDS-Page: Recombinant Human Calcineurin B Protein [NBP1-78797] - 15% SDS-PAGE (3 ug).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Calcineurin B Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-170 of Human Calcineurin B

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGNEASYPLE MCSHFDADEI KRLGKRFKKL DLDNSGSLSV EEFMSLPELQ QNPLVQRVID IFDTDGNGEV DFKEFIEGVS QFSVKGDKEQ KLRFAFRIYD MDKDGYISNG ELFQVLKMMV GNNLKDTQLQ QIVDKTIINA DKDGDGRISF EEFCAVVGGL DIHKKMVVDV

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PPP3R1
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
21.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human Calcineurin B Protein

  • Calcineurin B
  • calcineurin subunit B type 1
  • CALNB1
  • CNA2
  • Cnb1
  • MCIP1
  • PP2B beta 1
  • PPP3R1
  • Protein phosphatase 2B regulatory subunit 1
  • protein phosphatase 2B regulatory subunit B alpha
  • protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform(calcineurin B, type I)
  • protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform(calcineurin B, type I)
  • protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform
  • Protein phosphatase 3 regulatory subunit B alpha isoform 1
  • protein phosphatase 3, regulatory subunit B, alpha
  • type I (19kDa)

Background

PPP3R1, also known as Calcineurin subunit B type 1, is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway. Calcineurin is composed of two subunits; calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells. Recombinant human PPP3R1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-88218
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-66296
Species: Hu
NB120-2860
Species: Hu, Mu, Rt, Ba, Bv, Ch
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, ICC, IF
NBP1-98474
Species: Hu
Applications: WB
NBP2-58920
Species: Hu
Applications: WB, ICC/IF
NBL1-14708
Species: Hu
NB100-65214
Species: Hu, Mu, Rt, Ma
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
H00005478-M01
Species: Hu
Applications: WB, ELISA
NBP2-13304
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-86656
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-84425
Species: Hu, Mu
Applications: IHC, IHC-P
NBP1-32327
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB300-560
Species: Hu, Mu, Rt, Av, Bv, Pm
Applications: WB, IHC, IHC-Fr, IHC-P, IF
H00005555-P01
Species: Hu
NBP1-78797
Species: Hu
Applications: PAGE

Publications for Calcineurin B Recombinant Protein (NBP1-78797) (0)

There are no publications for Calcineurin B Recombinant Protein (NBP1-78797).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Calcineurin B Recombinant Protein (NBP1-78797) (0)

There are no reviews for Calcineurin B Recombinant Protein (NBP1-78797). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for Calcineurin B Recombinant Protein (NBP1-78797) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional Array Products

Bioinformatics Tool for Calcineurin B Recombinant Protein (NBP1-78797)

Discover related pathways, diseases and genes to Calcineurin B Recombinant Protein (NBP1-78797). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Calcineurin B Recombinant Protein (NBP1-78797)

Discover more about diseases related to Calcineurin B Recombinant Protein (NBP1-78797).
 

Pathways for Calcineurin B Recombinant Protein (NBP1-78797)

View related products by pathway.

PTMs for Calcineurin B Recombinant Protein (NBP1-78797)

Learn more about PTMs related to Calcineurin B Recombinant Protein (NBP1-78797).
 

Research Areas for Calcineurin B Recombinant Protein (NBP1-78797)

Find related products by research area.

Blogs on Calcineurin B

There are no specific blogs for Calcineurin B, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human Calcineurin B Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol PPP3R1