Cadherin-19 Antibody

Product Discontinued

Cadherin-19 Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human CDH19. The immunogen region is: Internal.
• Specificity: CDH19 Antibody detects endogenous levels of total CDH19 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDH19
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:20000
  • Western Blot 1:500-1:1000

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Cadherin-19 Antibody

• cadherin 19, type 2
• cadherin-19
• CDH7CDH7L2

Background

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDH19
• Uniprot:
  • Q9H159(Human)