CABP1 Antibody

Western Blot: CABP1 Antibody [NB100-1087] - Analysis of CABP1 in Human Brain lysate using this antibody at 1 ug/ml. Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

CABP1 Antibody Summary

• Immunogen: Peptide with sequence GNCVKYPLRNLS corresponding to N-Terminus according to NP_112482.1, NP_004267.2.
• Specificity: This antibody is expected to recognise both Human isoforms.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CABP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.5 - 2 ug/ml
• Application Notes: WB: Approx. 20 kDa band observed in human brain lysate (predicted MW of 19 kDa band).
• Control:

  Human Brain Whole Tissue Lysate (Adult Whole Normal)

• Control Peptide:

  CABP1 Peptide (NB100-1087PEP)

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CABP1 Antibody

• CaBP1
• CALBRAIN
• calcium binding protein 1
• calcium binding protein 5
• calcium-binding protein 1
• caldendrin
• HCALB_BR

Background

CABP belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This protein is only detected in retina and brain. Study of the mouse homolog demonstrated that groups of cells expressing this protein are located in the center or inner border of the inner unclear layer of retina. Two alternatively spliced variants encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CABP1 Antibody (NB100-1087)(1)

Publication using NB100-1087

• Yamaguchi K, Yamaguchi F, Miyamoto O et al. Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain. J Biol Chem 1999-02-05 [PMID: 9920909]

Bioinformatics

• Gene Symbol: CABP1
• Entrez:
  • 9478(Human)
• Uniprot:
  • NP_004267(Human)