beta-2 Adrenergic R/ADRB2 Antibody

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Western Blot: Beta 2 Adrenergic Receptor Antibody [NB120-13989] - E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

beta-2 Adrenergic R/ADRB2 Antibody Summary

Immunogen
Synthetic peptide: DFRIAFQELLC LRRSSLKAYGN GYSSNGNTGE QSGYHVEQEKE NKLLCEDLPGT EDFVGHQGTVP SDNIDSQGRNCS T, corresponding to amino acids 335-408 of Human Beta 2 Adrenergic Receptor (NP_000015.1).
Localization
Cell Membrane
Clonality
Polyclonal
Host
Chicken
Gene
ADRB2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for beta-2 Adrenergic R/ADRB2 Antibody

  • ADRB2
  • ADRB2R
  • ADRBR
  • adrenergic, beta-2-, receptor, surface
  • B2AR
  • B2ARADRB2R
  • BAR
  • beta-2 Adrenergic R
  • beta-2 adrenergic receptor
  • beta2 AdrenergicR
  • beta-2 AdrenergicR
  • Beta-2 adrenoceptor
  • Beta-2 adrenoreceptor
  • BETA2AR
  • catecholamine receptor

Background

This protein is Beta 2 Adrenergic Receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADRB2
Entrez
Uniprot