Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Unconjugated]

Images

 
Western blot shows lysates of IMR‑32 human neuroblastoma cell line and HEK293T human embryonic kidney cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human beta -1,4-Glucuronyltransferase 1/B4GAT1 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
724057
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Unconjugated] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human  beta -1,4-Glucuronyltransferase 1/B4GAT1 Antibody
Asp43-Cys415
Accession # O43505
Specificity
Detects human beta -1,4-Glucuronyltransferase 1/B4GAT1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) B3GNT2, rhB3GNT6, or rhB4GalT1 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
B4GAT1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/mL
Publications
Read Publication using
MAB6664 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Unconjugated]

  • B3GNT1
  • B3GN-T1
  • B4GAT1
  • beta-1,3-N-acetylglucosaminyltransferase bGnT-6
  • BETA3GNTI
  • EC 2.4.1.149
  • i-beta-1,3-N-acetylglucosaminyltransferase
  • iGAT
  • iGNT
  • MDDGA13
  • N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
  • Poly-N-acetyllactosamine extension enzyme
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1B3GNT6
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

Background

B3GNT1 ( beta -1,3-N-acetylglucosaminyltransferase 1; also iGnT) is a 50 kD member of the b3GnT family of enzymes. It is synthesized by sensory neurons, endothelial cells and skeletal muscle. In the trans-Golgi, it collaborates with B4GALT1 to generate a linear poly-N-acetyllactosamine sequence that can be incorporated into either N-linked or O-linked glycans. Human B3GNT1 is a 451 amino acid (aa) type II transmembrane protein. It contains an eight aa N-terminal cytoplasmic segment, an extended 28 aa transmembrane region (aa 9-36), and a 379 aa luminal domain (aa 37-415). Over aa 37-415, human B3GNT1 shares 97% aa identity with mouse B3GNT1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (MAB6664)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


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Bioinformatics

Gene Symbol B4GAT1
Uniprot