Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 724057
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Alexa Fluor® 647] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human β-1,4-Glucuronyltransferase 1/B4GAT1 Antibody
  Asp43-Cys415
  Accession # O43505
• Specificity: Detects human beta -1,4-Glucuronyltransferase 1/B4GAT1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) B3GNT2, rhB3GNT6, or rhB4GalT1 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Beta-1,3-N-Acetylglucosaminyltransferase 1/B3GNT1 Antibody (724057) [Alexa Fluor® 647]

• B3GNT1
• B3GN-T1
• B4GAT1
• beta-1,3-N-acetylglucosaminyltransferase bGnT-6
• BETA3GNTI
• EC 2.4.1.149
• i-beta-1,3-N-acetylglucosaminyltransferase
• iGAT
• iGNT
• MDDGA13
• N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
• Poly-N-acetyllactosamine extension enzyme
• UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1B3GNT6
• UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

Background

B3GNT1 ( beta -1,3-N-acetylglucosaminyltransferase 1; also iGnT) is a 50 kD member of the b3GnT family of enzymes. It is synthesized by sensory neurons, endothelial cells and skeletal muscle. In the trans-Golgi, it collaborates with B4GALT1 to generate a linear poly-N-acetyllactosamine sequence that can be incorporated into either N-linked or O-linked glycans. Human B3GNT1 is a 451 amino acid (aa) type II transmembrane protein. It contains an eight aa N-terminal cytoplasmic segment, an extended 28 aa transmembrane region (aa 9-36), and a 379 aa luminal domain (aa 37-415). Over aa 37-415, human B3GNT1 shares 97% aa identity with mouse B3GNT1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.