ARAP3 Antibody

• Reactivity: Hu, Mu, Po, Bv, Ca
• Applications: ELISA, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ARAP3 Antibody Summary

• Immunogen: Peptide with sequence CTSSPPSSQPLT corresponding to C-Terminus according to NP_071926.4.
• Localization: Nuclear
• Predicted Species: Mouse (100%), Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ARAP3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:50
  • Peptide ELISA Detection limit 1:4000
• Application Notes: IP successful usage on scirrhous human gastric cancer cell lines. WB successful usage on scirrhous human gastric cancer cell lines is reported in scientific literature (PMID: 210764690).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ARAP3 Antibody

• Arf and Rho GAP adapter protein 3
• arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
• ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
• ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containingprotein 3
• centaurin, delta 3
• centaurin-delta-3
• CENTD3
• cnt-d3
• DRAG1
• FLJ21065
• phosphoinositide binding protein
• PtdIns(34,5)P3-binding protein

Background

The ARAP3 gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrinhomology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton andcell shape. It is a specif

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ARAP3 Antibody (NB100-1315)(1)

Publication using NB100-1315

• Krugmann S, Anderson KE, Ridley SH et al. Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol Cell 2002-01-01 [PMID: 11804589]

Bioinformatics

• Gene Symbol: ARAP3
• Entrez:
  • 64411(Human)
• Uniprot:
  • NP_071926.4.(Human)