Recombinant Human AKAP7 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human AKAP7 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-81 of Human AKAP7

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGQLCC FPFSRDEGKI SEKNGGEPDD AELVRLSKRL VENAVLKAVQ QYLEETQNKN KPGEGSSVKT EAADQNGNDN ENNRK

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
AKAP7
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
11.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human AKAP7 Protein

  • A kinase (PRKA) anchor protein 7
  • AKAP 18
  • AKAP15
  • AKAP18A-kinase anchor protein 7 isoform alpha
  • AKAP-7 isoform gamma
  • AKAP-7 isoforms alpha and beta
  • A-kinase anchor protein 18 kDa
  • A-kinase anchor protein 7 isoform gamma
  • A-kinase anchor protein 7 isoforms alpha and beta
  • A-kinase anchor protein 7
  • A-kinase anchor protein 9 kDa
  • A-kinase anchor protein, 18-kD
  • A-kinase anchoring protein 18
  • protein kinase A anchoring protein 7
  • Protein kinase A-anchoring protein 7 isoform gamma
  • Protein kinase A-anchoring protein 7 isoforms alpha/beta

Background

AKAP7 (A-kinase anchor protein 7 isoform gamma isoform alpha), also known as AKAP18, belongs to the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAP 7 is expressed in brain, heart, lung, pancreas and skeletal muscle. AKAP 7 binds PKA to the plasma membrane, and permits functional coupling to the L-type calcium channel. Recombinant human AKAP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol AKAP7