AHI1 Antibody (J5)

Product Discontinued

AHI1 Antibody (J5) Summary

• Immunogen: C-terminal for AHI1 protein was used as the immunogen for this antibody.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AHI1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunofluorescence
  • Immunohistochemistry 1-5 ug/ml
  • Immunoprecipitation 1-2 ug
  • Western Blot 1-2 ug/ml

Packaging, Storage & Formulations

• Storage: Lyophilized antibody can be kept at 4C for up to 3 months and should be kept at -20C for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20C) or for long-term storage (-80C). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.1 ml water.

Alternate Names for AHI1 Antibody (J5)

• Abelson helper integration site 1 protein homolog
• Abelson helper integration site 1
• Abelson helper integration site
• AHI-1
• contatins SH3 and WD40 domains
• dJ71N10.1
• DKFZp686J1653
• FLJ14023
• FLJ20069
• JBTS3
• jouberin
• ORF1

Background

Jouberin (AHI1), encoding the Jouberin protein, is an alternatively spliced signaling molecule that contains seven Trp-Asp (WD) repeats, an SH3 domain, and numerous SH3-binding sites. The gene is expressed strongly in embryonic hindbrain and forebrain, and AHI1 may be required for both cerebellar and cortical development in humans. Defects in AHI1 are the cause of Joubert syndrome 3, an autosomal recessive brain congenital malformation. The exact function of the AHI1 gene is not yet known.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AHI1
• Uniprot:
  • Q8K3E5(Mouse)