Adenylate Cyclase 3 Antibody (1A12) [Alexa Fluor™ Plus 647]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: 1A12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

Adenylate Cyclase 3 Antibody (1A12) [Alexa Fluor™ Plus 647] Summary

• Immunogen: C-terminal peptide of rat Adenylate Cyclase 3, PAAFPNGSSVTLPHQVVDNP with a Cys added to the N-terminus to allow coupling to KLH.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADCY3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Adenylate Cyclase 3 Antibody (1A12) [Alexa Fluor™ Plus 647]

• AC3
• AC3EC 4.6.1.1
• AC-III
• ADCY3
• Adenylate Cyclase 3
• adenylate cyclase type 3
• Adenylate cyclase type III
• Adenylyl cyclase 3
• adenylyl cyclase, type III
• ATP pyrophosphate-lyase 3
• EC 4.6.1
• KIAA0511
• olfactive type

Background

ADCY3, also known as Adenylate cyclase type 3, is a 129 kDa 1,144 amino acid protein, and is involved in the formation of the secondary messenger protein, cAMP. This protein has also been shown to have interactions with STOML3, CAMK2G, PDE1A, PDE1C, and PDE2A in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY3 and cholera, alcoholism, tuberculosis, and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADCY3