Adenylate Cyclase 6 Antibody

Western Blot: Adenylate Cyclase 6 Antibody [NBP3-12233] - 1:500 antibody dilution in DiluObuffer. Apparent NW is 130 kDa.

Immunohistochemistry-Paraffin: Adenylate Cyclase 6 Antibody [NBP3-12233] - Rat heart.1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Immunohistochemistry-Paraffin: Adenylate Cyclase 6 Antibody [NBP3-12233] - Rat Heart. 1:100 dilution in IHC Blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 10X magnification.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Adenylate Cyclase 6 Antibody Summary

• Immunogen: Synthetic peptide corresponding to N-terminal amino acids 13-27 of rat Particulate Adenylyl Cyclase 6 protein. Peptide was covalently modified and conjugated to KLH. Sequence: DERKTAWGERNGQKR
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADCY6
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunocytochemistry/Immunofluorescence 1:100-1:200
  • Immunohistochemistry 1:100-1:200
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Adenylate Cyclase 6 Antibody

• AC6
• ADCY6
• Adenylate Cyclase 6
• adenylate cyclase type 6
• Adenylate cyclase type VI
• Adenylyl cyclase 6
• ATP pyrophosphate-lyase 6
• Ca(2+)-inhibitable adenylyl cyclase
• DKFZp779F075
• EC 4.6.1.1
• KIAA0422

Background

ADCY6, also known as Adenylate cyclase type 6, consists of a 1,168 amino acid long isoform that is 131 kDa and a shorter 1,115 amino acid isoform that is 125 kDa, and is involved in the encoding of a membrane-bound enzyme. This protein has also been shown to have interactions with ATXN1, GNAS, CHRNA7, RAF1, and ADCY1 in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY6 and cholera, ataxia, and adenoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADCY6